EEG-based Dynamic Brain Imaging and Brain-Computer Interface
基于脑电图的动态脑成像和脑机接口
Bin He（贺斌）
ABSRACT
Brain activity is distributed over the 3-dimensional volume and evolves in time. Mapping dynamic brain activation with high spatial resolution and high temporal resolution is of great importance for understanding the brain functions and aiding in the clinical diagnosis and management of brain disorders. Electroencephalography (EEG) is a noninvasive technique to probe brain dynamics, and has been developed into a three-dimensional functional imaging modality for dynamic brain mapping. EEG has also played a significant role in our attempt to decode brain intention controlling a computer or device. This talk will consist of two parts: First, we will discuss the fundamental concepts of EEG and its relationship with the underlying brain activity, how EEG source imaging can offer a noninvasive window probing brain dynamics, and clinical applications to epilepsy source localization. Next, we will discuss the concepts and principles of EEG based brain-computer interface, and present our recent progresses in noninvasive brain-computer interface for controlling a virtual and physical object including flying a drone and controlling a robotic arm by “thought”. The presentation will feature the recent results from the group, and discuss challenges and opportunities of brain-computer interface, for aiding paralyzed patients as a medical technology, as well as the general population as a human-machine interface technology.
大脑的活动分布在三维空间中并随时间而演变。而绘制具有高空间分辨率和高时间分辨率的动态脑内活动成像，对于理解脑功能以及协助临床诊断和治疗大脑疾病具有重要的意义。脑电图（EEG）作为一种探测脑动态的无创性技术，已经发展成为用于脑动态图绘制的一种三维功能成像方法。EEG在我们试图解码大脑如何控制计算机或设备的过程中也起着重要的作用。本次讲座报告包括两个部分：首先，我们将讨论EEG的基本概念和它与潜在脑活动之间的关系，以及EEG源成像是如何实现无创非侵入式脑动态探测的。其次，我们也将会探讨基于EEG脑机接口的概念和原理，并介绍我们在用于控制虚拟和现实对象的无创脑机接口领域的最新研究进展，包括通过意识实现无人飞行器和机械臂的控制。本次讲座报告内容将会围绕着课题组最新的研究成果，讨论脑机接口所面临的机遇与挑战，以及作为辅助瘫痪病人的医疗技术和普通大众触手可及的人机接口技术。
BIOGRAPHY
Professor Bin He is Trustee Professor of Biomedical Engineering, Electrical and Computer Engineering, and Neuroscience, and Head of Carnegie Mellon University’s Department of Biomedical Engineering. Dr. He has made significant contributions to the fields of neuroengineering and biomedical imaging, advancing electroencephalography to a three-dimensional dynamic functional imaging modality and for brain control of a computer and device. He is the sole editor of textbook “Neural Engineering” with its 3rd edition being published by Springer. His research has been recognized by a number of prestigious awards, including the IEEE William J. Molock Award (2019), the IEEE Biomedical Engineering Award (2017), the IEEE Engineering in Medicine and Biology Society Academic Career Achievement Award (2015), the International Federation of Clinical Neurophysiology Outstanding Research Award (2012), among others. Previously He was recognized by the Distinguished McKnight University Professorship of Biomedical Engineering and Medtronic-Bakken Endowed Chair for Engineering in Medicine at the University of Minnesota. Dr. He served as a Past President of the IEEE Engineering in Medicine and Biology Society, Chair of Publications Committee of American Institute of Medical and Biological Engineering, and serves as the Chair of the International Academy of Medical and Biological Engineering. He also served as Editor-in-Chief of IEEE Transactions on Biomedical Engineering from 2013-2018, and as a Member of NIH BRAIN Initiative Multi-Council Working Group from 2015-2019. He is an elected Fellow of International Academy of Medical and Biological Engineering, IEEE, American Institute of Medical and Biological Engineering, and Biomedical Engineering Society.
贺斌教授是生物医学工程系、电气与计算机工程系、神经科学系教授，美国卡耐基梅隆大学生物医学工程系主任。贺斌教授在神经工程学和生物医学成像领域做出了多个重要贡献，尤其是推进了脑电图三维动态功能成像模式以用于计算和相关设备的脑机控制。贺斌教授出版了英文学术独著《Neural Engineering》，目前由Springer出版社已再版第三版。贺斌教授荣获了多项著名学术荣誉奖项，包括IEEE William J. Molock 奖（2019）、IEEE生物医学工程奖（2017）、IEEE医学和生物工程学会学术职业成就奖（2015）、IEEE医学和生物工程学会杰出服务奖（2014）、国际临床神经生理学协会杰出研究奖（2012）等。此前，贺斌教授还曾荣任明尼苏达大学生物医学工程Distinguished McKnight University Professorship及Medtronic-Bakken Endowed Chair；曾任IEEE医学和生物工程学会前主席、美国医学与生物工程院（AIMBE）出版物委员会主席、国际医学与生物工程院（IAMBE）主席。贺斌教授于2013年至2018年担任IEEE Transactions on Biomedical Engineering期刊主编，并于2015年至2019年担任NIH BRAIN Initiative Multi-Council工作组委员。此外，贺斌教授也是多个学会和组织的会士（FELLOW），包括：International Academy of Medical and Biological Engineering, IEEE, American Institute of Medical and Biological Engineering, and Biomedical Engineering Society。