The International Contest of Innovation (iCAN’21) was held at 19th December, 2021 online. The International Finals attracted 16 scientific and technological innovation productions from China, Japan, Thailand, Germany, and Switzerland involving health monitoring, intelligent sensing, artificial intelligence, Driverless, science and technology, biomedical technology, etc. After fierce competition, the participants of the 2021 iCAN International Finals won two first prizes, six second prizes and six third prizes. Congratulations to them for their achievements in the 2021 Innovation International Competition. Thanks to all participants. At this difficult time, sincerely thank all the teams for their great support to iCAN.